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Menarini Group Presented Initial Safety and Efficacy Data from Phase 1b/2 ELEVATE and ELECTRA Combination Studies of ORSERDU® (Elacestrant) in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2023 San Antonio Breast Cancer Symposium

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ELEVATE and ELECTRA studies were designed with the objective to overcome different treatment resistance mechanisms and enhance patient outcomes with oral-oral combination options. A preliminary analysis of data in the phase 1b part of the ELEVATE trial demonstrates antitumor activity of the combination evaluating ORSERDU with inhibitors of the PI3K/AKT/mTOR pathway and CDK 4/6 inhibitors. Encouraging results from phase 1 ELECTRA, evaluating ORSERDU in combination with abemaciclib regardless of metastatic sites, show a tolerable and manageable safety profile with favorable preliminary efficacy.

FLORENCE, Italy and NEW YORK, Dec. 12, 2023 /PRNewswire/ — The Menarini Group ("Menarini"), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. ("Stemline"), a wholly-owned subsidiary of the Menarini Group, focused on bringing transformational oncology treatments to cancer patients, presented results from phase 1b/2 ELEVATE and ELECTRA clinical studies evaluating ORSERDU® (elacestrant) in combination with other treatments. Both the ELEVATE and ELECTRA studies were designed with the objective to overcome different resistance mechanisms and enhance patient outcomes with combination treatment options. Data was presented at the 2023 San Antonio Breast Cancer Symposium (SABCS), December 5-9, 2023.

The ELEVATE study is evaluating elacestrant in combination with inhibitors of the PI3K/AKT/mTOR pathway (everolimus and alpelisib) and cell-cycle pathway inhibitors (palbociclib, ribociclib, and abemaciclib). Results reported at SABCS 2023 include all combination data from Cohort 1 of the phase 1b portion of the study, with the therapies showing predictable safety profiles that were consistent with prior studies. Additional cohorts are currently under evaluation to assess pharmacokinetics (PK) and determine the recommended phase 2 dose (RP2D) for each combination. The full abstract (1576517) can be viewed here.

"It is encouraging to see positive initial safety results in various combination studies of ORSERDU, along with promising preliminary efficacy data in these trials," said Hope Rugo, MD, professor of medicine, Division of Hematology and Oncology at the University of California San Francisco Helen Diller Family Comprehensive Cancer Center. "We look forward to learning more about ORSERDU’s role in combination settings and its potential across the spectrum of metastatic breast cancer."

The ELECTRA study is evaluating elacestrant in combination with abemaciclib. Phase 1b of this study will also determine the recommended phase 2 dose (RP2D) of this combination in patients regardless of metastases sites.  Phase 2 will evaluate the benefit of the combination in patients with ER+/HER2- advanced or metastatic breast cancer with brain metastases since both compounds have demonstrated the ability to cross the blood-brain barrier. Results reported at SABCS 2023 include the three dose cohorts of the phase 1b portion of the study, showing a tolerable and manageable safety profile with favorable preliminary efficacy in these patients, regardless of the site of their metastases. The three cohorts have been completed with no patients experiencing dose limiting toxicities. No discontinuations have been observed for any patient beyond the observation period due to toxicity. Most common adverse events were diarrhea, nausea, and neutropenia/neutrophil count decreased. Only neutropenia was associated with grade 3 events with the combination; managed with standard dose reduction for abemaciclib. The full abstract (1576518) can be viewed here.

"People living with ER+ metastatic breast cancer are often faced with treatment resistance, causing a significant need for innovative new options," said Elcin Barker Ergun, CEO of the Menarini Group. "While this data is preliminary, we are committed to advancing our comprehensive research on ORSERDU in combination with other treatments, to potentially help enhance patient outcomes, with the goal of extending and improving the lives of people with this disease."

See here for details of the Menarini Group/Stemline Therapeutics’ full range of presentations at SABCS.

About The Elacestrant Clinical Development Program
Elacestrant is also being investigated in several clinical trials in metastatic breast cancer disease, alone or in combination with other therapies. ELEVATE (NCT05563220) is a phase 1b/2 clinical trial that will evaluate the safety and efficacy of elacestrant combined with alpelisib, everolimus, palbociclib, abemaciclib, and ribociclib. ELECTRA (NCT05386108) is an open-label phase 1b/2, multicenter study evaluating elacestrant in combination with abemaciclib in patients with ER+, HER2- breast cancer. The phase 2 portion evaluates this treatment regimen in these patients with brain metastases. ELCIN (NCT05596409) is a phase 2 trial evaluating the efficacy of elacestrant in patients with estrogen receptor positive (ER+), human epidermal growth factor receptor-2 negative (HER2-) advanced/metastatic breast cancer who received one or two prior hormonal therapies and no prior cyclin-dependent kinase targeting enzymes CDK4 and CDK6 inhibitor (CDK4/6i) in the metastatic setting. Elacestrant is also being evaluated in early breast cancer disease.

About ORSERDU (elacestrant)
U.S. Indication: ORSERDU (elacestrant), 345 mg tablets, is indicated for the treatment of postmenopausal women or adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.

Full prescribing information for the U.S. can be found at www.orserdu.com.

Important Safety Information
Warning and Precautions

Dyslipidemia: Hypercholesterolemia and hypertriglyceridemia occurred in patients taking ORSERDU at an incidence of 30% and 27%, respectively. The incidence of Grade 3 and 4 hypercholesterolemia and hypertriglyceridemia were 0.9% and 2.2%, respectively.  Monitor lipid profile prior to starting and periodically while taking ORSERDU.

Embryo-Fetal Toxicity: Based on findings in animals and its mechanism of action, ORSERDU can cause fetal harm when administered to a pregnant woman.  Advise pregnant women and females of reproductive potential of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with ORSERDU and for 1 week after the last dose. Advise male patients with female partners of reproductive potential to use effective contraception during treatment with ORSERDU and for 1 week after the final dose.

Adverse Reactions

Serious adverse reactions occurred in 12% of patients who received ORSERDU. Serious adverse reactions in >1% of patients who received ORSERDU were musculoskeletal pain (1.7%) and nausea (1.3%). Fatal adverse reactions occurred in 1.7% of patients who received ORSERDU, including cardiac arrest, septic shock, diverticulitis, and unknown cause (one patient each).
The most common adverse reactions (>10%), including laboratory abnormalities, of ORSERDU were musculoskeletal pain (41%), nausea (35%), increased cholesterol (30%), increased AST (29%), increased triglycerides (27%), fatigue (26%), decreased hemoglobin (26%), vomiting (19%), increased ALT (17%), decreased sodium (16%), increased creatinine (16%), decreased appetite(15%), diarrhea(13%), headache (12%), constipation (12%), abdominal pain (11%), hot flush (11%), and dyspepsia (10%).

Drug interactions

Concomitant use with CYP3A4 Inducers and/or inhibitors:  Avoid concomitant use of strong or moderate CYP3A4 inhibitors with ORSERDU. Avoid concomitant use of strong or moderate CYP3A4 inducers with ORSERDU.

Use in specific populations

Lactation: Advise lactating women to not breastfeed during treatment with ORSERDU and for 1 week after the last dose.
Hepatic Impairment: Avoid use of ORSERDU in patients with severe hepatic impairment (Child-Pugh C). Reduce the dose of ORSERDU in patients with moderate hepatic impairment (Child-Pugh B).
The safety and effectiveness of ORSERDU in pediatric patients have not been established.

To report SUSPECTED ADVERSE REACTIONS, contact Stemline Therapeutics, Inc. at 1-877-332-7961 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

About The Menarini Group
The Menarini Group is a leading international pharmaceutical and diagnostics company, with a turnover of over $4.4 billion and over 17,000 employees. Menarini is focused on therapeutic areas with high unmet needs with products for cardiology, oncology, pneumology, gastroenterology, infectious diseases, diabetology, inflammation, and analgesia. With 18 production sites and 9 Research and Development centers, Menarini’s products are available in 140 countries worldwide. For further information, please visit www.menarini.com.

About Stemline Therapeutics Inc.
Stemline Therapeutics, Inc. ("Stemline") a wholly-owned subsidiary of the Menarini Group, is a commercial-stage biopharmaceutical company focused on the development and commercialization of novel oncology therapeutics. Stemline commercializes ORSERDU® (elacestrant) in the U.S. and Europe, an oral endocrine therapy indicated for the treatment of postmenopausal women or adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy. Stemline also commercializes ELZONRIS® (tagraxofusp-erzs), a novel targeted treatment directed to CD123 for patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic cancer, in the United States and Europe, which is the only approved treatment for BPDCN in the U.S. and E.U. to date. Stemline also commercializes NEXPOVIO® (selinexor) in Europe, an XPO1 inhibitor for multiple myeloma. Stemline also has an extensive clinical pipeline of small molecules and biologics in various stages of development for a host of solid and hematologic cancers.

 

Source : Menarini Group Presented Initial Safety and Efficacy Data from Phase 1b/2 ELEVATE and ELECTRA Combination Studies of ORSERDU® (Elacestrant) in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2023 San Antonio Breast Cancer Symposium

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This content was prepared by our news partner, Cision PR Newswire. The opinions and the content published on this page are the author’s own and do not necessarily reflect the views of Siam News Network

Tata Power urges all to Embrace Mother Earth, Love Our Planet and Switch to Green and Clean Energy

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Tata Power urges all to Embrace Mother Earth, Love Our Planet and Switch to Green and Clean Energy

~ Launches new brand film – ‘DuniyaApneHawale’ timed in sync with COP 28, in keeping with the company’s ‘Sustainable is Attainable’ movement~

MUMBAI, India, Dec. 12, 2023 /PRNewswire/ — Tata Power, one of India’s largest integrated power companies has launched a new brand film – ‘DuniyaApneHawale’ promoting the message of "Embrace Mother Earth. Love Our Planet. Switch to Green and Clean Energy."

 


Tata Power urges all to Embrace Mother Earth, Love Our Planet and Switch to Green and Clean Energy

 

As Tata Power stays steadfast in its commitment to ‘Sustainable is Attainable’, this is another step towards inspiring citizens to make sustainable lifestyles a reality and underscore the importance of individual action and responsibility towards a cleaner, greener future.

As a responsible corporate, Tata Power is encouraging the adoption of green energy products and services for its large consumer base including corporate. It is also working on popularizing how a sustainable lifestyle is ‘attainable’ for millions of Indians through wide-scale adoption of affordable green solutions like rooftop solar, EV charging, solar microgrids, group captive solutions, pumped hydro power, smart home automation solutions to promote energy efficiency et al.

Along with Hindi, English, Gujarati, Marathi, Tamil and Kannada news and business channels, the campaign is live on digital and social media platforms, engaging the public with its message.

The film depicts the journey of a globe, demonstrating the abuse and damage that our planet goes through day in and day out thanks to a range of human activities such as deforestation, construction, industrialization, and urbanization. By the end of its journey, the globe is soiled and battered, until two children – representing the future generation – rescue it, clean it, and hug it – demonstrating the love and care that we need to have for our planet. The video concludes with a strong message: ‘Embrace Mother Earth. Love Our Planet. Switch to green and clean energy’ with the words "Hold Me Tight" being sung in the background.

Watch the film:

https://www.youtube.com/watch?v=3sqagRNk5HA (English)

https://www.youtube.com/watch?v=2IbqvgylAVM (Hindi)

Video Landing Page:

https://www.tatapower.com/embraceloveswitchsia.aspx 

Tata Power is committed towards becoming the country’s most preferred and trusted green energy brand. The company plans to achieve 70% capacity generation from clean and green energy sources by 2023 and achieve carbon net neutrality by 2045.

 

Source : Tata Power urges all to Embrace Mother Earth, Love Our Planet and Switch to Green and Clean Energy

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This content was prepared by our news partner, Cision PR Newswire. The opinions and the content published on this page are the author’s own and do not necessarily reflect the views of Siam News Network

Guide Sensmart was present at Big 5 Global 2023, advocating for the digitalization of inspections for building HVAC systems

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Guide Sensmart at the Big 5 Global 2023

WUHAN, China, Dec. 11, 2023 /PRNewswire/ — As the largest HVACR exhibition in the Middle East, the Big 5 Global 2023 was grandly held at the Dubai World Trade Centre in the United Arab Emirates from December 4th to December 7th. The four-day event attracted outstanding HVAC equipment manufacturers, suppliers, and industry experts from around the world to witness this industry event together.


Guide Sensmart at the Big 5 Global 2023

 


Online thermography

Guide Sensmart showcased its online monitoring, handheld thermal imaging products, and multi-industry application solutions at this exhibition. Not only did they present handheld thermal cameras that can be widely used for building HVAC testing and equipment fault detection, but Guide Sensmart’s online thermography products can also conduct 24-hour online monitoring for applications such as power energy, safety monitoring, and industrial temperature measurement. When there are abnormal temperature changes, it can quickly locate the abnormal areas, immediately push alarm information and images to the intelligent display and control platform, and enable inspection personnel to quickly review and handle them. Through extensive data collection and verification, it achieves comprehensive monitoring with an extremely low daily false alarm rate

In addition, the Consumer Electronics Show (CES) will be held at the Las Vegas Convention Center in the United States from January 9th to 12th, 2024. Guide Sensmart will exhibit new thermal cameras and infrared application solutions for smart manufacturing, consumer electronics, and smart homes. Visitors are welcome to experience the extraordinary charm of infrared thermal imaging at booth 21844 in Central Hall.

About Guide Sensmart 
Guide Sensmart is a manufacturer of systematic infrared thermal imaging products, with a marketing service network covering 70 countries and regions worldwide. For more information, please visit https://www.guideir.com/.

Source : Guide Sensmart was present at Big 5 Global 2023, advocating for the digitalization of inspections for building HVAC systems

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WiMi Developed Holographic Complex Amplitude Computation and Update Technology

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BEIJING, Dec. 11, 2023 /PRNewswire/ — WiMi Hologram Cloud Inc. (NASDAQ: WIMI) ("WiMi" or the "Company"), a leading global Hologram Augmented Reality ("AR") Technology provider, today announced that it successfully developed a new technology—-"Holographic Complex Amplitude Computation and Updating Technology", which utilizes the complex amplitude calculation method to achieve real-time updating and accurate reconstruction of holograms, and through the latest algorithms and sensing technologies, the holographic display system is able to deal with complex computational tasks more efficiently and provide a latency-free interactive experience. This technology is a breakthrough in the field of holographic display interaction.

The key feature of WiMi’s holographic complex amplitude computation and updating technology is that it can draw and erase 3D point cloud images in real-time and without delay, while enabling the observer to freely perform drawing and erasing operations in 3D space. This is based on complex amplitude computation, where the complex amplitude represents the amplitude and phase information of light waves, which is a key element in realizing accurate holographic displays. By using a motion sensor to detect the position of the observer’s fingertip, the system is able to calculate the complex amplitude distribution of the hologram. Unlike conventional methods, this technique is independent of the number of points that make up the 3D point cloud in each frame, allowing the system to update the hologram quickly, even as the number of points in the cloud increases.

This technique aims to address the limitations of existing holographic display systems in terms of real-time computation and interactive drawing. Through the accurate calculation and updating of complex amplitude, the technique enables holograms to be reconstructed at a much higher speed, realizing real-time drawing and erasing for interaction with the observer’s fingertips, which greatly enhances the user’s interactive experience in 3D space. The technology utilizes an advanced motion sensor system to accurately capture the position of the observer’s fingertip, and realizes the rapid reconstruction of holograms through the computation and updating of the complex amplitude distribution. The characteristics of holographic complex amplitude, combined with the latest algorithmic optimization, ensure that the system remains stable and efficient when processing large-scale 3D point cloud images.

The framework of the holographic complex amplitude computation and updating technology is a combination of several key components that together form an efficient, real-time holographic display system. The system framework includes:

Sensor and localization: The motion sensor in the system is responsible for capturing the position of the observer’s fingertips and gesture movements. Through precise positioning technology, the system can accurately capture the observer’s gesture trajectory in the air, realizing real-time tracking and positioning of drawing and erasing operations in 3D space.

Complex amplitude computation: This module is responsible for computing the complex amplitude distribution of holograms. Using the complex amplitude computation method, the system is able to accurately describe the amplitude and phase information of light waves, thus realizing the accurate reconstruction and updating of the hologram. The efficient computation of this module ensures the real-time accuracy of the hologram.

Holograms updating engine: The holograms updating engine is the core component of the system, which is responsible for handling the computation and updating of the complex amplitude distribution. It adopts high-speed parallel computing technology, which can quickly handle large-scale computing tasks and realize real-time updating of holograms. The engine ensures that the system is able to quickly update the holograms in every frame, enabling the observer to enjoy a latency-free interactive experience.

Projection and display devices: In order to allow the observer to see the real-time drawing and erasing (interactive) process of the holograms, the system is equipped with high-resolution projection and display devices. These devices are capable of accurately reproducing complex holograms and projecting them into the air for the observer to visualize and interact with.

Interactive interface and user feedback: The system is designed with an intuitive user interface and provides real-time user feedback. By accurately recognizing and responding to the observer’s gestures, the system is able to display the effects of the observer’s drawing and erasing operations in the air in real-time, allowing the user to control the interaction process of the holograms in a more intuitive way.

The launch of the holographic complex amplitude computation and updating technology will bring a far-reaching impact to the holographic display field. According to the person in charge of the enterprise, the release of this innovative technology marks the enterprise’s leading position in the field of holographic display, and also demonstrates its determination and ability to continuously promote scientific and technological innovation. In the future, we will continue to increase R&D investment in holographic display technology to bring users more high-quality, immersive visual experiences, and help holographic display technology to be widely used and developed in various fields.

WiMi’s holographic complex amplitude computation and updating technology is expected to be applied to holographic-graphic near-eye displays, head-mounted displays (HMDs), and other augmented reality (AR) and virtual reality (VR) applications, further expanding the possibilities of user interfaces and mobile devices. and provide strong support for next-generation user interfaces and mobile devices. This technology is expected to enable contactless interfaces, allowing users to draw and erase characters freely in the air, creating a more immersive and intuitive user experience. It is believed that holographic display technology will usher in a whole new era of development, bringing people a more realistic and stunning visual experience, and helping to drive the vigorous development of the digital era.

About WIMI Hologram Cloud

WIMI Hologram Cloud, Inc. (NASDAQ:WIMI) is a holographic cloud comprehensive technical solution provider that focuses on professional areas including holographic AR automotive HUD software, 3D holographic pulse LiDAR, head-mounted light field holographic equipment, holographic semiconductor, holographic cloud software, holographic car navigation and others. Its services and holographic AR technologies include holographic AR automotive application, 3D holographic pulse LiDAR technology, holographic vision semiconductor technology, holographic software development, holographic AR advertising technology, holographic AR entertainment technology, holographic ARSDK payment, interactive holographic communication and other holographic AR technologies.

Safe Harbor Statements

This press release contains "forward-looking statements" within the Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," and similar statements. Statements that are not historical facts, including statements about the Company’s beliefs and expectations, are forward-looking statements. Among other things, the business outlook and quotations from management in this press release and the Company’s strategic and operational plans contain forward−looking statements. The Company may also make written or oral forward−looking statements in its periodic reports to the US Securities and Exchange Commission ("SEC") on Forms 20−F and 6−K, in its annual report to shareholders, in press releases, and other written materials, and in oral statements made by its officers, directors or employees to third parties. Forward-looking statements involve inherent risks and uncertainties. Several factors could cause actual results to differ materially from those contained in any forward−looking statement, including but not limited to the following: the Company’s goals and strategies; the Company’s future business development, financial condition, and results of operations; the expected growth of the AR holographic industry; and the Company’s expectations regarding demand for and market acceptance of its products and services.

Further information regarding these and other risks is included in the Company’s annual report on Form 20-F and the current report on Form 6-K and other documents filed with the SEC. All information provided in this press release is as of the date of this press release. The Company does not undertake any obligation to update any forward-looking statement except as required under applicable laws.

Source : WiMi Developed Holographic Complex Amplitude Computation and Update Technology

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Kyrie Irving Announces Investment In KICKS CREW, The World's Fastest-Growing Sneaker Community And Marketplace

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8x NBA All-Star Kyrie Irving Joins KICKS CREW as Chief Community Officer and Investor

 8x NBA All-Star Joins Startup as Chief Community Officer, Kicking Off 11 Days Of Giving Philanthropic Initiative with ANTA Shock Wave 5 Giveaway

NEW YORK, Dec. 12, 2023 /PRNewswire/ — KICKS CREW, the leading global digital marketplace for authentic sneakers and apparel, announces an investor partnership with international basketball athlete, artist, and actor Kyrie Irving today. Irving will join KICKS CREW as an equity shareholder and assume the role of Chief Community Officer.


8x NBA All-Star Kyrie Irving Joins KICKS CREW as Chief Community Officer and Investor

Fresh from signing a new brand partnership with ANTA and unveiling his new logo, Irving has invested in KICKS CREW because of its track record and commitment to building a player-owned and empowered platform. The partnership is driven by a mutual desire to democratize the sneaker marketplace and unite communities through sneaker culture.

Kyrie Irving’s role as Chief Community Officer will also showcase a cause-driven, community-centric approach, empowering new brands and collaborations that blend art and basketball in new ways. His efforts will extend globally, including initiatives and projects to positively impact the Middle East and Africa, embodying a broader social and cultural engagement vision.

"I’m excited to partner and invest in KICKS CREW’s vision to empower a new generation of independent consumers and thinkers. This is an empowerment play for my fellow entrepreneurs, artists, and athletes who have and want their independent visions and approaches celebrated. My role as Chief Community Officer at KICKS CREW is centered around the mission of bringing all communities together through their love of sneaker culture to push forward unity and philanthropy," said Kyrie Irving when discussing his new investment.

Since its inception, KICKS CREW has been a champion for emerging brands, serving as a nexus for sneaker companies growing their international reach. It has also been a platform for NBA players to establish and grow their personal brands. KICKS CREW’S vision for a player-centric platform serves as a springboard for making Irving’s products more accessible to fans.

"We are thrilled to welcome Kyrie Irving into the KICKS CREW family and for us to be accepted into the A11Even Tribe," says KICKS CREW co-founder Ross Adrian Yip. "Kyrie’s influence on the community and deep passion for philanthropy brings immeasurable value to bringing our vision to life, and we are eager to use our platform to empower Kyrie and many more players willing to leverage their independent influence."

Kyrie Irving has chosen to kick off his yearly 11 Days Of Giving Initiative with KICKS CREW to celebrate this new partnership and investment. Irving and KICKS CREW are giving away 111 pairs of the ANTA Shock Wave 5 from December 11th to December 15th, 2023. Fans can sign up to enter the giveaway on the Kyrie Irving x KICKS CREW event page


Kyrie Irving Kicks Off Yearly 11 Days Of Giving Initiative with KICKS CREW

Complete list of every ANTA Shock Wave 5 available to win:

ANTA Shock Wave 5 Pro "Halloween"

ANTA Shock Wave 5 Pro "Dark Knight"

ANTA Shock Wave 5 Pro "Smriti"

ANTA Shock Wave 5 Pro "Championship"

ANTA Shock Wave 5 Pro "Lone Ranger"

ANTA Shock Wave 5 "Inherit"

ANTA Shock Wave 5 "Dark Matter"

ANTA Shock Wave 5 "Sand Lizard"

ANTA Shock Wave 5 "Immortality"

ANTA Shock Wave 5 "Mutations"

ANTA Shock Wave 5 "Grey"

Kyrie Irving started the NBA season sporting the ANTA Shock Wave 5 Pro, showcasing ANTA’s latest flagship product. The entire ANTA Shock Wave 5 collection is now available on KICKS CREW. Kyrie Irving’s first signature shoe with ANTA is expected to launch in the first half of 2024.

DOWNLOAD HIGH-RES VISUALS THROUGH THIS LINK

ABOUT KICKS CREW

Launched in January 2021, KICKS CREW is a trusted global marketplace with the broadest selection of sneakers and apparel. KICKS CREW operates on a unique business model by only directly working with verified retailers and brands to ensure authenticity is at the source for customers. With a fast-growing global audience, KICKS CREW has partnered with the most significant international sporting brands for direct product launches. With world-class investor backing (Gobi Partners, AEF, and Pacific Century Group), KICKS CREW emphasizes community engagement and accessibility by offering a borderless shopping experience to millions of users worldwide.

ABOUT KYRIE IRVING

Kyrie Irving is a professional basketball player in the NBA on the Dallas Mavericks. He attended Duke University before being selected as the first overall pick in the 2011 NBA Draft by the Cleveland Cavaliers. Kyrie played a pivotal role in securing an NBA Championship with the Cleveland Cavaliers in 2016. Beyond basketball, Kyrie is known for his philanthropic efforts and artistic ventures, reflecting a multifaceted personality beyond the basketball court.

 

Source : Kyrie Irving Announces Investment In KICKS CREW, The World's Fastest-Growing Sneaker Community And Marketplace

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STRADVISION CTO, Jack Sim, Unveils Innovative Deep Learning Development Methodology at Tech.AD USA 2023

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STRADVISION CTO, Jack Sim, presented a groundbreaking study, "Efficient Deep Learning Development through Teacher-Student Learning and Sprints and Its Application to 3D Perception Systems," at Tech.AD USA 2023.


Efficient Deep Learning: CTO Jack Sim unveils a streamlined development process through teacher-student learning and sprints Swift Product Releases: Reduces development time by 50%, enabling rapid creation of ImmersiView™ and monthly software releases Adaptable 3D Perception: The methodology extends to build versatile 3D perception systems, showcasing adaptability to diverse sensor inputs

SEOUL, South Korea, Dec. 12, 2023 /PRNewswire/ — STRADVISION, an automotive industry pioneer in deep learning-based vision perception technology, announced today that its CTO, Jack Sim, presented a groundbreaking study, "Efficient Deep Learning Development through Teacher-Student Learning and Sprints and Its Application to 3D Perception Systems," at Tech.AD USA 2023. The event, focused on ‘level 3 to X autonomy & autonomous vehicle technologies,’ took place from December 6 to 8, 2023, at The Henry, Dearborn, Michigan.


STRADVISION CTO, Jack Sim, presented a groundbreaking study, "Efficient Deep Learning Development through Teacher-Student Learning and Sprints and Its Application to 3D Perception Systems," at Tech.AD USA 2023.

In his presentation, Sim unveiled an efficient software development process for multiple deep-learning tasks, leveraging teacher-student learning and sprints. This methodology, concurrently improving accuracy and speed, resulted in a remarkable reduction of product development time by up to 50%.

The process was successfully applied in the creation of STRADVISION’s augmented reality product, ImmersiView™. Sim explained that the approach decouples dependencies between tasks, trains individual teacher networks in sprints for improved accuracy, and employs a unified student network for simultaneous task learning.

"To optimize accuracy while maintaining inference speed constraints, STRADVISION applied neural architecture search to the student network in the initial sprints and subsequently fixed the architecture in the remaining sprints," Sim explained. This efficient process enabled the first prototype creation within three months, followed by consistent monthly software releases.

The methodology was further extended to address the challenges of building multi-modal 3D perception systems, demonstrating its adaptability and effectiveness in handling diverse sensor inputs during training. Sim emphasized, "This approach ensures comprehensive and accurate perception, exemplifying the adaptability and effectiveness of our development process in handling diverse sensor inputs in training."

Jack Sim concluded, "Our research underscores the significance of our method in advancing the field of multi-modal perception in autonomous systems, paving the way for the future of automotive technology."

STRADVISION continues to lead the way in deep learning-based vision perception technology, driving innovation and setting new standards for efficient and adaptive development processes.

About STRADVISION 

Founded in 2014, STRADVISION is an automotive industry pioneer in artificial intelligence-based vision perception technology for ADAS. The company is accelerating the advent of fully autonomous vehicles by making ADAS features available at a fraction of the market cost compared with competitors. STRADVISION’s SVNet is being deployed on various vehicle models in partnership with OEMs; can power ADAS and autonomous vehicles worldwide; and is serviced by over 300 employees in Seoul, San Jose, Detroit, Tokyo, Shanghai, and Dusseldorf. STRADVISION has been honored with Frost & Sullivan’s 2022 Global Technology Innovation Leadership Award, the Gold Award at the 2022 and 2021 AutoSens Awards for Best-in-Class Software for Perception Systems, and the 2020 Autonomous Vehicle Technology ACES Award in Autonomy (software category). In addition, STRADVISION and its software have achieved TISAX’s AL3 standard for information security management, as well as being certified to the ISO 9001:2015 for Quality Management Systems and ISO 26262 for Automotive Functional Safety. 

Source : STRADVISION CTO, Jack Sim, Unveils Innovative Deep Learning Development Methodology at Tech.AD USA 2023

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HEYTEA Brews Success on Broadway: Inaugural US Store Achieves Record Sales and Sparks "HEYTEA Buzz" in NYC

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HEYTEA Brews Success on Broadway: Inaugural US Store Achieves Record Sales and Sparks “HEYTEA Buzz” in NYC

The Broadway debut marks HEYTEA’s successful entry into the U.S. market, showcasing commitment to delivering authentic tea products and joy-inspiring brand experiences

NEW YORK, Dec. 11, 2023 /PRNewswire/ — On December 8, HEYTEA’s inaugural store in the United States officially opened on Broadway, New York City, and witnessed a warm reception from New York consumers, achieving a remarkable sales volume of 2,500 cups on the opening day.

This marks HEYTEA’s continued expansion in the international market, following its previous entry into countries i.e., the United Kingdom, Australia, and Canada. Through dedicated efforts to provide global users with Chinese new style tea products, HEYTEA is actively implementing its goal of delivering authentic tea products and joy-inspiring brand experiences to an even wider audience.


HEYTEA Brews Success on Broadway: Inaugural US Store Achieves Record Sales and Sparks “HEYTEA Buzz” in NYC

HEYTEA Buzz Sweeping New York City

On the opening day, HEYTEA made a prominent appearance on the Times Square billboard in New York City. The brand’s youthful and trendy image not only revitalized the traditional perception of tea beverages among American consumers but also sparked a "HEYTEA buzz" within local communities. The opening day garnered enthusiastic crowds, as eager consumers formed lengthy queues to indulge in the new style tea offerings. Notably, the store achieved a milestone with sales of 2,500 cups on its inaugural day of operation.

Tea lovers eagerly shared their HEYTEA experiences on platforms like RED, TikTok, and Instagram, showcasing signature products such as the Very Grape Cheese (Original) and Roasted Brown Bobo Milk (Original). This further solidifies HEYTEA’s brand momentum in the dynamic landscape of New York City.

HEYTEA’s widespread popularity can be attributed to the introduction of its innovative next-generation tea products. It has been revealed that HEYTEA’s in-store offerings include a diverse array of fresh fruits and juices, a selection of customized tea bases sourced from various tea-producing regions in China, and 100% fresh milk. Notably distinct from the prevalent use of instant powdered ingredients such as non-dairy creamer and tea powder in traditional tea beverages in the current U.S. market, these high-quality and fresh materials and unique product formulations deliver a revolutionary and elevated experience to American consumers.

Chinese New Style Tea Originator Going Global

Since 2012, HEYTEA has been pioneering the new style tea industry by introducing innovative products such as Cheese Tea, which combines fresh tea leaves with premium cheese. Since then, the new style tea sector has experienced rapid growth. Currently, the international tea beverage market, including the United States, is entering a high-growth phase. According to Verified Market, the U.S. tea drink market was estimated at around 505 million USD in 2021 and is estimated to grow to 833 million USD by 2030, with a compound annual growth rate (CAGR) of 7.42%.

HEYTEA’s debut on Broadway underscores the brand’s confidence in the American tea drinks market. It also showcases HEYTEA’s unwavering commitment to provide premium products and services to American consumers. "We eagerly anticipate the opportunity to introduce top-notch products and services to American consumers through our authentic tea offerings and joy-inspiring brand experiences," said Yujia Gu, VP of Strategy at HEYTEA. "Our goal is to drive an upgrade in the product landscape and continuously expand the space within the American tea drinks market."

HEYTEA has been accelerating its overseas business expansion since 2023. Starting from August 2023, HEYTEA has consecutively opened its first stores in several new international markets, including the United Kingdom, Australia, Canada, and others, comprehensively expediting its business and brand development overseas. Currently, HEYTEA boasts a global presence of over 3,000 stores.

About HEYTEA

HEYTEA is the originator of new style tea. In 2012, HEYTEA began under humble circumstances in Jiangbianli, Guangdong, China. Armed with the principal of using only REAL ingredients and NO artificial flavors or colorants, HEYTEA created the first Cheese Tea by blending cheese foam with fresh tea. With its mission and vision of "Promoting Quality, Living Joy," HEYTEA is committed to rejuvenating traditional tea culture and making high-quality tea products available to all consumers. In 2018, HEYTEA opened its first international store in Singapore, bringing new style tea to a larger global community. Currently, HEYTEA has more than 3,000 stores worldwide.

For more information about HEYTEA, please visit: www.heytea.com.

Source : HEYTEA Brews Success on Broadway: Inaugural US Store Achieves Record Sales and Sparks "HEYTEA Buzz" in NYC

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This content was prepared by our news partner, Cision PR Newswire. The opinions and the content published on this page are the author’s own and do not necessarily reflect the views of Siam News Network

2023 Dishui Lake Emerging Finance Conference Begins: Lin-Gang Equity Cluster Launched

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Key Financial Players Gather to Strategize on Enhancing Financial Strength at Emerging Finance Summit.

SHANGHAI, Dec. 11, 2023 /PRNewswire/ — On December 8, 2023, the Dishui Lake Emerging Finance Conference commenced at Lingang Center in Shanghai. Chen Jinshan, a member of the Standing Committee of the Municipal Committee of the CPC, Secretary of the Party Working Committee and Director of the Management Committee of Lin-Gang Special Area, attended the event.

In October, China’s Central Financial Work Conference outlined an agenda to establish the nation as a financial powerhouse, focusing on financial solutions that are technologically advanced, eco-friendly, inclusive, supportive of retirement schemes and fully digital, while emphasizing increased openness. President Xi Jinping, during his Shanghai visit, underscored the city’s central role, as mandated by the Central Committee, to rapidly transform the city into a center for commerce, finance, trade, shipping, and innovation in technology. In response, Shanghai is enhancing its financial institutions and infrastructure and advocating for greater financial transparency. The initiative includes efforts in the Lin-Gang area to conduct stress testing, expand regulatory and governance frameworks, and elevate standards for cross-border trade and investment.

The Lin-Gang Special Area has lent additional significance to the Dishui Lake Emerging Finance Conference by serving as the host. The conference seeks to leverage the area’s pioneering financial models and establish a more practical and effective platform for cooperation within the emerging financial sector, enhancing Shanghai’s international standing as a financial hub and furthering the nation’s financial objectives.

The conference included an electrifying inauguration, a gathering of industry giants for a captivating keynote address, three engaging panel discussions, a series of seminars, and a thematic exhibition that showcased the emerging trends in the finance sector in Lin-Gang. The event’s 50 sessions, emphasizing international reach, diversity, professionalism, practicality, and influence, served as a platform for engaging dialogue between financial institutions, special economic zones, and the private sector.  

At the inauguration, the Lin-Gang Special Area Equity Investment Cluster was officially launched. Directed by the municipal government and party committee, Lin-Gang focuses on supporting the real economy, emphasizing technological innovation, and advancing industries. The area targets investment in small, promising startups, offering funding at various development stages. Policies on fundraising, investing, managing, and exiting are slated for further optimization, aiming to attract more investment firms to Shanghai and drive Lin-Gang’s long-term growth.

At the conference, Yuan Guohua, Deputy Secretary of the CPC Working Committee of the Lin-Gang Special Area, CPC Committee Secretary, and Chairman of Lingang Group, presented the "Vision and Actions of Emerging Finance in Lin-Gang to Boost China’s Financial Power" initiative. The Lingang Emerging Finance Development Report was unveiled.

The keynote session featured six eminent experts and academic leaders, including Asian Infrastructure Investment Bank chief economist Erik Bergolf and former International Monetary Fund vice president John Lipsky. The session highlighted their collective expertise and insights in economics.

To forge a financial powerhouse and foster advanced financial development, Lin-Gang Special Area is prioritizing comprehensive reforms and greater transparency through the build of a platform for communication and exchange focused on emerging financial sectors. Collaborating with financial services, banks, brokerages and insurers, it plans to organize a series of resource-sharing events. The aim is to advance structural reforms on the financial supply side and develop a modern financial ecosystem. A key objective is to position Dishui Lake Financial Bay as a catalyst for financial openness and innovation. The initiative is expected to significantly contribute to Shanghai’s stature as an international financial center and the broader development of the Lin-Gang Special Area, further enhancing the impression of "Dishui Lake, the Global Financial Bay".

Source : 2023 Dishui Lake Emerging Finance Conference Begins: Lin-Gang Equity Cluster Launched

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This content was prepared by our news partner, Cision PR Newswire. The opinions and the content published on this page are the author’s own and do not necessarily reflect the views of Siam News Network