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Frost & Sullivan Names Motorola Solutions Product Leader in the Global Body-Worn Camera Market

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Motorola Solutions’ V700 and VB400 body-worn cameras strengthen transparency and trust with best-in-class connectivity, evidence management, and integrated smart sensors

SAN ANTONIO, Nov. 8, 2023 /PRNewswire/ — Following a thorough assessment of the global body-worn camera market, Frost & Sullivan named Motorola Solutions (NYSE: MSI) the recipient of the 2023 Global Product Leadership Award in the body-worn camera market. The company’s V700 and VB400 body-worn cameras outperform competitive solutions with their dependable connectivity and battery life, AI-enabled evidence platform, and smart sensors and integrations that connect the cameras to the company’s broader technology ecosystem.

Pranav Sahai, commercial and public security industry analyst at Frost & Sullivan, stated, "Frost & Sullivan named Motorola Solutions the global product leader in body-worn cameras for their high-quality video and audio that ensures the reliability of footage, digital signatures that protect evidential integrity, connected sensors that can trigger the camera to record should an officer be in danger and the V700’s ability to stream real-time footage to command via mobile broadband. The V700 and VB400’s unique capabilities help to enhance officer and community safety and increase transparency."

Motorola Solutions’ newest body-worn camera, the V700, is equipped with mobile broadband connectivity, allowing live video streaming to command centers to improve real-time awareness without the need of Wi-Fi. The VB400’s wide-angle, high-definition 1080p camera is highly configurable, and operators can modify its controls to match jurisdictional needs. It is globally available to public safety and private organizations.

The V700 connects to an end-to-end ecosystem of public safety technology, including CommandCentral Aware—the company’s cloud-based platform that unifies data, video, and voice to offer a common operating picture—M500 in-car video systems, and APX radios. Both cameras also integrate with Holster Aware sensors. Agencies can set triggers to record, such as if an officer does not respond to a fallen radio alert or if a weapon is removed from its holster, increasing officer safety and community transparency.

The V700 and VB400 also help law enforcement document evidence. A key differentiator of the company’s VideoManager software is its advanced digital signature technology that verifies recordings, making it nearly impossible to tamper or modify footage. Completing the workflow, CommandCentral Evidence uses AI to transcribe footage and auto redact, saving officers time and protecting community privacy.

Elizabeth Whynott, Frost & Sullivan best practices research analyst, added, "For law enforcement and security personnel today, body-worn cameras are an essential tool to capture evidence and ensure transparency, and we expect to see continued growth in their adoption. Motorola Solutions’ cost effective body-worn cameras are easy to use and integrate seamlessly into existing public safety technology, making the V700 and VB400 cameras of choice and positioning the company for continued growth."

Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid market acceptance. The award recognizes the quality of the solution and the customer value enhancements it enables.

Frost & Sullivan Best Practices awards recognize companies in various regional and global markets for demonstrating outstanding achievement and superior performance in leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analyses, and extensive secondary research to identify best practices in the industry. This is the first year Frost & Sullivan has named a Global Product Leadership Award recipient in the body-worn cameras market, recognizing a high-quality body-worn camera that drives customer value with innovative features, functionality, and enhancements.

About Frost & Sullivan
For six decades, Frost & Sullivan has been world-renowned for its role in helping investors, corporate leaders, and governments navigate economic changes and identify disruptive technologies, Mega Trends, new business models, and companies to action, resulting in a continuous flow of growth opportunities to drive future success. Contact us: Start the discussion.

Contact:
Ashley Weinkauf
P: 1.210.844.2505
E: ashley.weinkauf@frost.com

Source : Frost & Sullivan Names Motorola Solutions Product Leader in the Global Body-Worn Camera Market

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Clarifai Hires Jonathan Padgett to Lead Public Sector Sales

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WASHINGTON, Nov. 8, 2023 /PRNewswire/ — Clarifai is excited to announce they have hired Jonathan Padgett as their Vice President of Public Sector Sales. With three decades of experience in software sales and industry knowledge, in his new role, Jonathan will oversee the growth of Public Sector sales and the expansion of governmental partnerships.

Most recently Jonathan oversaw UIPath’s public sector business which resulted in over $20M in sales and expanded their customer base to over 75 U.S. Federal customers in three and a half years. Jonathan brings a significant amount of experience doing business development with federal civilian and defense agencies, which aligns with Clarifai’s focus on being the full stack AI platform partner of choice across the U.S. Government.

Before UIPath, Jonathan held senior business development roles at OpenText, IBM, Microsoft, and Adobe. He holds a music education and business degree from the Musicians Institute of Technology.

"I’m incredibly proud of the pioneering efforts Clarifai has done over the last ten years to create the industry’s first full stack AI platform. With multiple proof points of the platform in use across the U.S. government at all classification and technology readiness levels, and many DOD, Intelligence, and Civilian agencies, we are thrilled to have Jonathan take our public sector business to the next level. His deep experience in building out public sector businesses and driving hyper-growth is critical to drive the next steps of our growth at Clarifai," stated Matt Zeiler, Founder and CEO of Clarifai.

As Clarifai celebrates 10 years of success and technology innovation such as full motion video,  satellite imagery analysis, document intelligence, and AI Lake in the public sector, this marks the onset of the next phase of its growth forged by strategic partnerships.

About Clarifai
Clarifai provides the full stack AI platform for developers and teams to quickly and collaboratively get vision, language, and audio AI into production with our secure, privacy-enabled, and scalable hybrid cloud offering. Clarifai enables enterprises and public sector organizations to extract insights rapidly from their unstructured data and, in doing so, increase the value of their data and human capital, reduce AI expenses, and do so with enterprise-friendly AI governance. By significantly reducing the necessity for specialist data science knowledge, we democratize AI technology, lowering entry barriers and encouraging adoption across different sectors. Founded in 2013 by Matt Zeiler, Ph.D., Clarifai has been recognized by leading industry analysts, Forrester, Gartner, and IDC, and has been a market leader in AI since winning the top five places in image classification at the 2013 ImageNet Challenge. For more information, please visit: www.clarifai.com

Contact: claudia.ziegler@clarifai.com

Source : Clarifai Hires Jonathan Padgett to Lead Public Sector Sales

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OPPO and Hasselblad Announced to Co-Develop the Next Generation of HyperTone Camera Systems Following Aesthetics

OPPO and Hasselblad Announced to Co-Develop the Next Generation of HyperTone Camera Systems Following Aesthetics

PARIS, FRANCE – Media OutReach – 8 November 2023 – At Paris Photo 2023, one of the world’s largest international art fairs dedicated to photography, Global technology brand OPPO and the legendary camera manufacturer, Hasselblad, today announced a joint venture to co-develop the next generation of HyperTone Camera Systems in 2024. Following aesthetics, HyperTone Camera Systems will usher in a new era in computational photography. The systems will initially arrive in future Find series flagships, providing users with an unprecedented mobile imaging experience beyond imagination.

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OPPO Imaging Director Oliver Zhang said: “Thanks to the HyperTone Camera System which follows aesthetics, the Find X6 Series is positively received by both the public and professionals. With Find N3 Series, we also brought flagship-level imaging experience for foldables for the first time. I am delighted that our collaboration with Hasselblad has now entered a new phase. By combining classic imaging aesthetics with mobile technology, OPPO and Hasselblad have developed an aesthetic system that is tailored for mobile imaging. In 2024, the two companies will launch the next generation HyperTone Camera Systems and Hasselblad camera experience that promise to continue to set new industry standards.”

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Bronius Rudnickas, Hasselblad Global Marketing Manager, said: “We are very pleased to see OPPO’s latest advancements in mobile imaging, which allow people to use their smartphone to bring their creativity to life through photography. Our continued collaboration to build the next-generation HyperTone Camera Systems is a huge project, that is not just a simple inheritance of style. Instead, it is a more organic and in-depth integration of the aesthetics and technology between both brands that will provide photography enthusiasts with enhanced image quality and stylized experiences, beyond what’s achievable on typical mobile phones. I am looking forward to sharing the results of our collaboration with all the creators next year.”

Bronius Rudnickas.jpg

Following aesthetics, OPPO is leading a revolution in mobile imaging

As a pioneer in mobile imaging, OPPO is leading a revolution by following aesthetics rather than relying on industry traditions of certain technical specifications. This new approach allows the objective technical process to serve the subjective aesthetic of users.

The Photography Aesthetics Feature Quantification Lab is made up of 10% photography technicians, 50% professional photographers, and 40% color experts. Through feature breakdown, solutions planning, and precise tuning, OPPO has created a new photography technology development system, ushering in a new era in computational photography.

HyperTone Camera System

OPPO’s HyperTone Camera System consists of HyperTone All Main Camera System, HyperTone Image Engine, and HyperTone ProXDR Display, to deliver end-to-end system-level imaging capabilities. In addition to Find series flagships, the technical architecture of HyperTone Camera System will empower multiple OPPO product series in the future, for flagship imaging experience with consistent aesthetics and exceptional quality.

To meet users’ mobile imaging needs, HyperTone Camera System offers the first-ever All Main Camera System in the industry. It enables high image qualities for every focal length whether it’s day or night. In the Find N3, OPPO brings the stack pixel technology sensor to foldable phones for the first time, achieving performance similar to a one-inch sensor that can be fitted into a foldable.

Following aesthetics, HyperTone Image Engine solves many issues in traditional computational photography, achieving fewer digital artifacts with more computation. Extra HD Algorithm, for example, improves clarity by 30% while reducing noise by 60% by using AI RAW fusion. The new algorithm requires 400% more computing power, but it results in cleaner and clearer details after processing.

Photo viewing is an indispensable part of a great imaging experience. HyperTone Camera System comes with the industry-leading HyperTone ProXDR Display. By precisely recording the brightness of 12 million pixels, ProXDR technology can unlock up to eight times more dynamic range on-screen, restoring the natural tone to make viewing photos much more realistic. Additionally, OPPO is also working to make ProXDR compatible with the Ultra HDR standard.

Hasselblad Portrait Mode

Portrait is not only one of the most popular camera features, but it also represents the most cutting-edge innovation of computational photography. Following aesthetics, Hasselblad Portrait Mode provides portrait photography effects that lead the industry.

Through the HyperTone Engine, Hasselblad Portrait Mode initiates delicate tonal changes to create a three-dimensional portrait that avoids brightening the face too much and smoothing out light and shadow. By optimizing with 45 times more skin tone colors, Hasselblad Portrait Mode offers more accurate skin tones. And with Bokeh Flare Portrait, users can get a cinematic bokeh effect that truly simulates the optical out-of-focus effect.

Work shot using OPPO phones at Paris Photo

In 2023, OPPO launched the imagine IF Project to break through the existing limitations of mobile imaging with global users. As a key part of the project, the OPPO imagine IF Photography Awards 2023 has received over 700,000 submissions from 51 countries and regions.

The 26th Paris Photo event will be held in Paris, France between November 9-14, 2023. As the only smartphone brand participating in Paris Photo this year, OPPO presented a series of exceptional images, including the works of world-class photographers and the winning works from the OPPO imagine IF Photography Awards 2023. OPPO’s presence at Paris Photo serves as a bridge for fostering cross-cultural communication, revealing new possibilities of mobile imaging to photographers, collectors and artists worldwide.

Norwegian photography artist and Hasselblad Master, Tina Signesdottir Hult, acclaimed photography artist and Hasselblad master, Wang Jianjun, renowned fashion photographer and Hasselblad Ambassador, Yin Chao, OPPO imagine IF Photography Awards 2023 winner, Ahei Huan, as well as many other photographers, will attend the festival to witness the first presentation of their work shot using OPPO phones at Paris Photo.

Hashtag: #OPPO

The issuer is solely responsible for the content of this announcement.

About OPPO

OPPO launched the “Smiley Face Phone” in 2008, continuing to show technological goodwill and moving forward with a smile. Today, OPPO is innovating the personal technology experience with its Find N folding flagship, Find X imaging flagship and other mobile phones, multiple smart devices such as OPPO Watch and OPPO Pad, and the ColorOS software system. OPPO adheres to technological innovation and operates in more than 60 countries and regions around the world. More than 30,000 OPPO employees are committed to creating a better and smarter life for people.

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This content was prepared by Media OutReach. The opinions expressed in this article are the author's own and do not reflect the view of Siam News Network.

PVEL Updates Extended Reliability Testing Program

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PVEL

The independent lab announces changes to the flagship PV Module Product Qualification Program

NAPA, Calif., Nov. 9, 2023 /PRNewswire/ — PV Evolution Labs (PVEL), the leading independent test lab for the downstream solar industry and member of the Kiwa Group, today announced upgrades to the company’s suite of extended reliability and performance tests, the Product Qualification Program (PQP). PVEL established the PQP in 2012 to provide empirical data for PV module benchmarking and project-level energy yield and financial models, and to help recognize top performing PV modules.


PVEL’s 2023 PQP Module Test Sequence

PVEL’s PQP testing helps inform the company’s annual PV Module Reliability Scorecard, which provides actionable insights for PV module procurement based on data from PVEL’s industry-leading testing.

"The module buying landscape has changed dramatically in recent years with advancements in module technology and new players entering the market, and in response, PVEL has focused our globally-acclaimed test program on addressing these changes," said Tristan Erion-Lorico, VP of Sales and Marketing at PVEL. "The improvements we’ve made in this PQP update incorporate critical feedback from our downstream partners, research institutes, module and component manufacturers, and our own test results, keeping the PVEL PQP at the forefront of the growing demand for PV module procurement due diligence."

Notable updates to the PQP include:

A new test to address concerns around Ultraviolet Induced Degradation (UVID) Refocusing the Hail Stress Sequence (HSS) on identifying the threshold of glass breakage Modifying the Mechanical Stress Sequence (MSS) to target module mechanical durability concerns Streamlining processes for Light Induced Degradation (LID), Damp Heat (DH), Light and Elevated Temperature Induced Degradation (LETID), and Backsheet Durability Sequence (BDS) testing

"PVEL is committed to providing the data that matters for a strong solar industry," said Kevin Gibson, Managing Director at PVEL. "We’re confident that our updated PQP will help accelerate test timelines while helping buyers around the world to make better informed procurement decisions."

Participation in PVEL’s PQP is voluntary for manufacturers and only top-performing module model types are named in the annual PVEL Scorecard. To date, PVEL has tested over 600 BOMs from more than 70 manufacturers for the PV Module PQP.

About PVEL

PVEL, a member of the Kiwa Group, is the leading reliability and performance testing lab for downstream solar project developers, financiers, and asset owners around the world. PVEL and the Kiwa Group provide a suite of technical services for mitigating risk, optimizing financing and improving system performance throughout the project lifecycle. For over a decade, PVEL’s flagship Product Qualification Program has replaced assumptions about PV module performance with quantifiable metrics, and connected manufacturers with a global network of 400+ downstream partners. Learn how PVEL makes data matter though PQP testing, field services and market intelligence at pvel.com.

 

 

Source : PVEL Updates Extended Reliability Testing Program

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TAILG's New Brand TLG Makes Spectacular Debut at EICMA in Milan, Italy

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Inaugurating its Presence in Europe, TLG Unveils First Flagship Store in Switzerland

MILAN, Nov. 9, 2023 /PRNewswire/ — On November 8, TAILG showcased its new brand at EICMA, Italy’s premier exhibition for motorcycles. The company unveiled TLG to a global audience and simultaneously inked a deal to open its first European flagship store in Switzerland.

TAILG ‘s new TLG brand makes spectacular debut

TLG, drawing on TAILG’s over 20 years of R&D expertise in the two and three-wheeled electric vehicle sector, was created to meet the demands of urban commuting with electric bikes and scooters. Embodying the ethos of Try · Love · Go, the brand is dedicated to shaping a personalized, intelligent urban travel lifestyle.

The four founders of TAILG took to the stage to unveil the new brand at the launch event.

Sun Muchai, Senior Vice President of TAILG, highlighted that TLG, backed by TAILG ‘s extensive technological expertise and intelligent manufacturing infrastructure in the electric vehicle sector, embodies the group’s unwavering commitment to global markets.

TAILG has consistently been dedicated to exploring green, low-carbon and eco-friendly concepts, with a focus on the experience of riders worldwide using electric two-wheel transportation. As an electric mobility partner of the United Nations Environment Programme (UNEP), TAILG has consistently collaborated with UNEP to actively champion the principles of low-carbon mobility and electric mobility solutions across the globe for many years.

"TAILG is committed to providing users with smart short-distance travel solutions that embody simplicity, elegance, intelligence, and agility. We also aspire to deliver a technologically sophisticated, resilient, and enduring brand and product experience while placing significant emphasis on community culture and engagement. We hope that consumers will fall in love it from the first ride," added Mr. Sun.

Multiple new products make their worldwide debut

As a global trendsetter for two-wheelers, TAILG ‘s decision to launch the new TLG brand at EICMA holds great significance. In recent years, the global two-wheeled vehicle market has experienced rapid growth, especially in Europe, with France, Germany, Italy, and the Netherlands leading the way.

In a bid to offer European consumers superior low-carbon, eco-friendly short-distance travel solutions, TLG has strategically positioned itself in the mid-to-high-end markets and has been committed to providing customized products based on local regional characteristics, user habits and market segments, with a focus on E-Bikes and E-scooters.

During the launch event, several new products, including the GTS, CTS and TL6, were unveiled.

Simultaneously, a strategic cooperation agreement on TLG’s first European flagship store was formally signed by TAILG and the business partner. The 400-square-meter venue will soon open in Switzerland and be the first in Europe where local consumers can quickly experience new TLG products following their launch.

At the EICMA 2023, TAILG also unveiled several new TAILG offerings, including the S1, S2, and ETS, which are ideal for city dwellers, as well as the TY3 and TY3 PRO, two off-road racing models designed specifically for young enthusiasts. These releases provide consumers with a broad range of product options.

About TAILG

Founded in 2004 in Shenzhen, China, TAILG is a global technology group company which integrates the research and development, production, sales, sharing, and charging & swapping of electric vehicles, and other whole industry chain services. Relying on the high-standard R&D center, TAILG owns more than 1,000 national patents and operates nine production bases in China and has an annual production capacity of over 12 million vehicles. It also has more than 30,000 terminal experience stores and exports to more than 90 countries and regions worldwide.

For more information, please visit https://www.tailg.com/.

Source : TAILG's New Brand TLG Makes Spectacular Debut at EICMA in Milan, Italy

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Frost & Sullivan Honors Leading Organizations with Prestigious Industry Awards at the 2023 Best Practices Awards Ceremony

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2023 Best Practices APAC Awards Banquet

Sixteen Companies Awarded Excellence in Best Practices by Frost & Sullivan for Best-in-Class Performance

KUALA LUMPUR, Malaysia, Nov. 9, 2023 /PRNewswire/ — The 2023 Frost & Sullivan Best Practices Awards Ceremony took place at the St. Regis Hotel in Kuala Lumpur, Malaysia, bringing together companies from the APAC and MEASA region that have accomplished innovative or disruptive breakthroughs while continually demonstrating tremendous achievements in their respective industries.


2023 Best Practices APAC Awards Banquet

Frost & Sullivan bestows its Best Practices Awards upon companies that serve as catalysts for industry growth. "They are the trailblazers," remarked Jeff Frigstad, Global Senior Vice President of Best Practices at Frost & Sullivan. "It brings me great pleasure to extend my heartfelt congratulations to all the well-deserving winners for their top-tier achievements. We aspire that their recognition will inspire others to pursue innovation and excellence."

Twenty Awards were presented at the ceremony:

AdaniConneX – 2023 South Asia Data Center Infrastructure and Operations Company of the Year Award
Cellcard (CAMGSM Plc.) – 2023 Cambodia Mobile Services Product Leadership Award
CHT Security Co., Ltd. – 2023 Taiwan Cybersecurity Services Company of the Year Award
Chunghwa Telecom Co., Ltd. – 2023 Taiwan 5G Services Customer Value Leadership Award
Chunghwa Telecom Co., Ltd. – 2023 Taiwan Data Center Services Company of the Year Award
Chunghwa Telecom Co., Ltd. – 2023 Taiwan Telecoms Company of the Year Award
CUCKOO – 2023 Malaysia Home Water Purifier Company of the Year Award
George Clinical – 2023 Asia-Pacific Contract Research Organization Competitive Strategy Leadership Award
Gleneagles Hospital Kuala Lumpur – 2023 Malaysia Hospital Customer Value Leadership Award
Kerry Logistics Network Limited – 2023 Asia-Pacific Logistics Company of the Year Award
Novotech – 2023 Asia-Pacific Contract Research Organization Company of the Year Award
Petromin Express – 2023 Saudi Arabia Automotive Quick Services Competitive Strategy Leadership Award
Siro Clinpharm Private Limited – 2023 India Contract Research Organization Customer Value Leadership Award
Smart Axiata Co., Ltd. – 2023 Cambodia Mobile Data Services Company of the Year Award
Smart Axiata Co., Ltd. – 2023 Cambodia Mobile Services Company of the Year Award
Smart Selangor Delivery Unit – 2022 Southeast Asia Smart City Governance Agency Company of the Year Award
ST Telemedia Global Data Centres (Thailand) – 2023 Thailand Data Center Services Company of the Year Award
Sunway Medical Centre Velocity – 2023 Malaysia Emerging Hospital Company of the Year Award
Teleperformance – 2023 Asia-Pacific Customer Experience Outsourcing Services Company of the Year Award

Frost & Sullivan Best Practices awards recognize companies each year in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analyses, and extensive secondary research to identify best practices.

To learn more about the awards, please visit https://www.frost.com/analytics/best-practices-recognition/. To schedule an interaction with a Frost & Sullivan spokesperson, please email Tarini Singh at [email protected].

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, collaborates with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today’s market participants. For more than 50 years, Frost & Sullivan has been developing growth strategies for the global 1000, emerging businesses, the public sector, and the investment community.

Contact us: Start the discussion.

 

Source : Frost & Sullivan Honors Leading Organizations with Prestigious Industry Awards at the 2023 Best Practices Awards Ceremony

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QS World University Rankings: Asia 2024

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Best Universities in Asia Revealed

LONDON, Nov. 9, 2023 /PRNewswire/ — The QS World University Rankings: Asia 2024, evaluating  academic and employer recognition, research prowess, teaching resources and internationalisation, is the largest ever, showcasing 857 institutions from 25 countries and territories, including 149 newcomers. Peking University retains its title as Asia’s best university for a second consecutive year, followed by The University of Hong Kong and the National University of Singapore in second and third place, respectively.  India emerges as Asia’s most represented nation, boasting 148 ranked universities—a significant increase of 30 from last year. Mainland China follows with 133, and Japan features 96. Myanmar, Cambodia, and Nepal are included for the first time.

 

Asia Top 20

2024

2023

Location

1

1

Peking University

CN

2

4

The University of Hong Kong

HK

3

2

National University of Singapore

SG

=4

5

Nanyang Technological University

SG

=4

3

Tsinghua University

CN

6

6=

Zhejiang University

CN

7

6=

Fudan University

CN

8

12=

Yonsei University

KR

9

15

Korea University

KR

10

12=

Chinese University of Hong Kong

HK

=11

10

Shanghai Jiao Tong University

CN

=11

9

Universiti Malaya

MY

13

8

KAIST

KR

14

11

The University of Tokyo

JP

15

14

HKUST

HK

16

17

Seoul National University

KR

=17

23

City University of Hong Kong

HK

=17

16

Kyoto University

JP

19

18

Sungkyunkwan University

KR

20

22

Tohoku University

JP

 

China leads as Asia’s premier research hub, with 24 universities ranked in the top 50 for Citations per Paper, reflecting their high-impact research. India shines for research volume with seven universities in the top 10 for Papers per Faculty and is noted for its high proportion of staff holding PhDs.

Japan maintains strong international reputation among employers and academics. Kazakhstan leads in Central Asia with one university in the top 100.

Singapore’s higher education remains at the forefront in Asia, with two universities in the top five and marked research impact. South Korea demonstrates academic excellence, with two of its universities rising into the top 10.

Malaysia is recognised for its outstanding internationalisation efforts. Iran leads Asia in research productivity and staff with PhDs. Indonesia and Thailand shine for high proportion of International Faculty, and Vietnam achieves its best performance in employer reputation.

Ben Sowter, QS Senior VP, said: "This year’s rankings affirm that perseverance in enhancing academic standards and research quality is pivotal for the progress of Asia’s higher education sector."         

 

Source : QS World University Rankings: Asia 2024

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Allgenesis Announces Encouraging Preliminary Safety and Efficacy Data from the AG-73305 Phase 2a Trial for the Treatment of Diabetic Macular Edema at American Academy of Ophthalmology

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TAIPEI, Nov. 8, 2023 /PRNewswire/ — 

AG-73305 was found to be safe and tolerable with no severe adverse effects (SAEs) after a single intravitreal injection of doses of 0.5, 1, 2, and 4 mg in DME patients. Data combining all 4 cohorts showed mean improvement in Best Corrected Visual Accuity (BCVA) of +6.4 ETDRS letters with mean Central Subfield Thickness (CST) improvements of -100 microns at 4 weeks post-injection. The efficacy lasted up to 24 weeks after a single injection of AG-73305.  Kaplan-Meier analysis showed approximately 66% probability that patients did not require rescue by 24 weeks.

Allgenesis Biotherapeutics Inc. presented exciting preliminary data from the first-in-human, Phase 2a clinical trial assessing the safety, tolerability, and efficacy of AG-73305 in Diabetic Macular Edema (DME) patients.  The data was presented as a paper presentation at the 2023 American Academy of Ophthalmology (AAO) conference, which was held from November 2 to 6 in San Francisco, CA.  

Preliminary data from the 22-patient study demonstrated that AG-73305, a bi-functional Fc-fusion protein designed to block VEGF and integrin pathways, was safe and tolerable after a single intravitreal injection.  There were no dose-limiting toxicities and no SAEs related to AG-73305 in patients. Efficacy assessments for the 4 cohorts showed a mean improvement in BCVA of +6.4 ETDRS letters with CST reduction of -100 microns 4 weeks after the injection.  The effects lasted between 12 and 24 weeks after a single injection and Kaplan-Meier analysis showed approximately 66% probability that patients did not require rescue by 24 weeks. "We are very excited to share this preliminary data at AAO and we are equally encouraged that our data and approach was well-received by the ophthalmology community." said Madhu Cherukury, Ph.D., DABT., CEO of Allgenesis. "The data from our Phase2a study supports the hypothesis that blocking multiple pathways in the disease state can provide additional benefits to DME patients in the form of BCVA gains with the potential to push for the extend durability vs. current standard of care."

"We are extremely encouraged by the safety and efficacy outcomes after just one intravitreal injection, with 54.5% of patients seeing 10 or more letter improvements", said Sunil Patel MD, PhD., Chief Medical Officer. "Given its novel mechanism of action, AG-73305 has the potential to be a disease modifying therapy for retinal diseases and the next generation treatment option for DME patients."

"Given the positive data that we are seeing from the open label study, we are forging ahead with the next phases of our development plans and looking forward to unlock the true potential of AG73305 in a Phase 2b study in DME patients." said Dr. Cherukury.

In September 2021, Allgenesis announced it entered into a licensing agreement with AffaMed Therapeutics for the development and commercialization of AG-73305 in Greater China, South Korea, and multiple ASEAN markets.

About AG-73305

AG-73305 is a humanized, bi-specific Fc-fusion protein designed to simultaneously block VEGFs and integrins for the treatment of DME, nAMD, RVO, and other retinal diseases. AG-73305 contains a VEGF-trap and a disintegrin that blocks various key integrin receptors. AG-73305 has the potential to treat both anti-VEGF responders and non-responders. The Phase 2a first-in-human study is expected to be completed in March 2024.

About Allgenesis Biotherapeutics Inc.

Allgenesis is a clinical-stage biopharmaceutical company headquartered in Taiwan. The company is focused on research and development of novel medicines for the treatment of eye diseases. Current projects in the pipeline include AG-73305, a potential blockbuster drug for the treatment of DME, nAMD, and other retinal diseases such as RVO, and AG-80308 for Dry Eye Disease.

Source : Allgenesis Announces Encouraging Preliminary Safety and Efficacy Data from the AG-73305 Phase 2a Trial for the Treatment of Diabetic Macular Edema at American Academy of Ophthalmology

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This content was prepared by our news partner, Cision PR Newswire. The opinions and the content published on this page are the author’s own and do not necessarily reflect the views of Siam News Network