An easy, secure and private way to accept contactless payments with only an iPhone and the Zeller App, no additional hardware is required.

MELBOURNE, Australia, Oct. 31, 2023 /PRNewswire/ — Zeller, the Australian fintech reimagining business banking, today enabled businesses using Zeller to seamlessly and securely accept in-person contactless payments using Apple’s Tap to Pay on iPhone contactless payment acceptance technology, and the Zeller App.

Tap to Pay on iPhone and Zeller App

Tap to Pay on iPhone accepts all forms of contactless payments, including, contactless credit and debit cards, Apple Pay, and other digital wallets, using only an iPhone and the Zeller App — no additional hardware or payment terminal is needed.

At checkout, the merchant will simply prompt the customer to hold their contactless credit or debit card, iPhone or Apple Watch to pay with Apple Pay, or another digital wallet near the merchant’s iPhone, and the payment will be securely completed using NFC technology. Tap to Pay on iPhone also supports PIN entry, which includes accessibility options.

Apple’s Tap to Pay on iPhone technology uses the built-in features of iPhone to keep the business’ and customers’ data private and secure. When a payment is processed, Apple doesn’t store card numbers on the device or on Apple servers.

Benefits of Zeller’s Tap to Pay on iPhone offering for business owners include:

No additional hardware or apps required: Business owners can accept contactless payments with only their iPhone and the Zeller App, eliminating the need for a card reader and the hassle of downloading a separate app. Ease of getting started and simplicity of use: They can easily use Tap to Pay on iPhone with the Zeller App. They simply need to log in, enter a payment amount, and have the customer tap their contactless card or smartphone to the merchant’s iPhone. Access industry-leading payment features within the Zeller App: Business owners can enjoy Zeller’s industry-leading payment technology, which includes features like built-in tipping, surcharging, transaction notes, digital receipts, and more. Businesses can also manage their finances, accept contactless payments, open transaction accounts, issue debit cards, and track performance, all from their iPhone. Affordable pricing: One low, flat transaction fee for all cards, including American Express, and no monthly subscription fees. Plus, business owners get their money faster with nightly settlement to their Zeller Account, 365 days a year. Secure contactless payments: Tap to Pay on iPhone ensures fast and secure contactless payments, backed by Zeller’s industry-leading security for the protection of business and customer data.

"Zeller’s launch of Tap to Pay on iPhone is a significant step forward in our mission to simplify financial management for businesses of all sizes. By offering Tap to Pay on iPhone within the Zeller App — our dedicated business super app — we’re offering increased efficiency for our customers, who can accept payments, manage finances, and streamline operations all from their iPhone. This is a game-changer for business owners at every stage," commented Ben Pfisterer, Zeller CEO and co-founder.

Tap to Pay on iPhone enables Zeller customers to use a contactless payment acceptance solution that is easy to set up and use. On an iPhone XS or later running the latest version of iOS, merchants can simply download the Zeller App from the Apple App Store to get started accepting contactless payments within minutes.

For more information on Tap to Pay on iPhone using Zeller, please visit https://www.myzeller.com/zeller-app/tap-to-pay/iphone 

About Zeller

Zeller is reimagining business banking for Australian businesses. Formed in 2020, Zeller enables businesses to accelerate their cash flow through integrated tools to accept payments, manage their finances, and pay recipients fast. Zeller is co-founded by Ben Pfisterer and Dominic Yap, who bring extensive financial services experience from global companies including Square, Visa, NAB, and more. The company is backed by Square Peg, Apex Capital Partners, Addition, Spark Capital, Headline, and Hostplus.

Source : Zeller launches Tap to Pay on iPhone for business owners to accept contactless payments with Zeller iOS App

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NEW YORK, Oct. 31, 2023 /PRNewswire/ — SunCar Technology Group Inc. (the "Company" or "SunCar") (NASDAQ: SDA), a leading provider of digitalized enterprise automotive after-sales services and online auto insurance intermediation services in China, today announced it closed its previously announced follow-on offering of $21 million of Class A Ordinary Shares, par value $0.0001 per share (the "Ordinary Shares") at a price of $8.18 per share. The Company issued a total of 2,567,238 Ordinary Shares to certain institutional investors. As part of the transaction, the Company issued to the investors certain common warrants ("Common Warrants") for the purchase of up to 3,850,857 Ordinary Shares at an exercise price of $9.00 per share, which Common Warrants have a term of five years from the date of issuance. The net proceeds to the Company from this offering are approximately $19 million, after deducting placement agent fees and other estimated offering expenses.

FT Global Capital, Inc. acted as the exclusive placement agent for the transaction.

Pryor Cashman LLP acted as counsel to the Company and ArentFox Schiff LLP acted as counsel to the placement agent in connection with the offering. 

The Company intends to use the net proceeds from this offering for working capital and general corporate purposes.

These securities are being offered through a prospectus contained in the Company’s effective registration statement on Form F-1 (Filing No. 333-275144) which was declared effective by the Securities and Exchange Commission (the "SEC") on October 25, 2023. A final prospectus related to the offering has been filed with the SEC and is available for free on the SEC’s website at www.sec.gov. 

This press release does not constitute an offer to sell or the solicitation of an offer to buy, and these securities cannot be sold in any state in which this offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of any such state. Any offer will be made only by means of a prospectus forming a part of the effective registration statement.

About SunCar Technology Group Inc.

Originally founded in 2007, SunCar is transforming the customer journey for car insurance and aftermarket services in China, the largest passenger vehicle market in the world. SunCar develops and operates online platforms that seamlessly connect drivers with a wide range of automotive services and insurance coverage options through a nationwide network of provider partners. As a result, SunCar has established itself as the leader in China in the B2B automotive after-sales services market and the online insurance market for electric vehicles. The company’s multi-tenant, cloud-based platform empowers its enterprise clients to optimally access and manage their customer database and offerings, and drivers gain access to hundreds of services from tens of thousands of independent providers in a single application. For more information, please visit: https://suncartech.com. 

Forward-Looking Statements

This press release contains information about the Company’s view of its future expectations, plans and prospects that constitute forward-looking statements. Actual results may differ materially from historical results or those indicated by these forward-looking statements as a result of a variety of factors including, but not limited to, risks and uncertainties associated with its ability to raise additional funding, its ability to maintain and grow its business, variability of operating results, its ability to maintain and enhance its brand, its development and introduction of new products and services, the successful integration of acquired companies, technologies and assets into its portfolio of products and services, marketing and other business development initiatives, competition in the industry, general government regulation, economic conditions, dependence on key personnel, the ability to attract, hire and retain personnel who possess the technical skills and experience necessary to meet the requirements of its clients, and its ability to protect its intellectual property. The Company encourages you to review other factors that may affect its future results in the Company’s annual reports and in its other filings with the Securities and Exchange Commission.

Contact Information:

SunCar:
Investor Relations: Ms. Hui Jiang
Email: [email protected]  
Legal: Ms. Li Chen
Email: [email protected]

U.S. Investor Relations
Matthew Abenante, IRC
President
Strategic Investor Relations, LLC
Tel: 347-947-2093
Email: [email protected] 

Source : SunCar Technology Group Inc. Announces the Closing of $21 Million Follow-on Offering

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– Board Special Committee receives several indications of interest from financial sponsors and strategic buyers 

– Board to confirm plans for special meeting, pending outcome of November 21 court hearing on an injunction application against Ace Lead Profits and its Hollysys shares

BEIJING, Oct. 30, 2023 /PRNewswire/ — Hollysys Automation Technologies Ltd. (NASDAQ: HOLI) ("Hollysys" or the "Company") today announced that the Special Committee of the Board of Directors, which was established to conduct a sale process as announced on October 2, and its advisors have been in contact with multiple prospective buyers. These include financial sponsors as well as strategic buyers for which there would be compelling industrial logic to an acquisition.

Additionally, the Special Committee and its advisors are considering bids submitted by Recco Control Technology and Dazheng Group (Hong Kong) Investment Holdings Company (collectively, the "Recco Consortium") and by representatives of the Hollysys management team. It is engaged in ongoing discussions with both groups and will provide updates on material developments as soon as practicable.

In a statement, the members of the Special Committee stated: "We are making every effort to conduct a fair and full process and to be fully responsive to all current and potentially interested parties to facilitate due diligence and enable them to make updated and binding proposals. Our objective is to present to shareholders a recommended proposal that provides compelling value, committed financing, regulatory certainty, and a viable pathway to closing."

The sale process is targeted to be at an advanced stage, with a preferred bidder identified, as soon as early December.

Further Update on Special Meeting Request

As previously announced, on October 20, 2023, the Company received updated materials from requisitioning shareholders with respect to a request to convene a special meeting of shareholders.

While the requisition shareholders were on the register as of the demand record date of September 6, 2023, there is currently a dispute (to which the Company is not a party) over the ownership and control of Ace Lead Profits Limited and its shares in the Company, which is subject to an injunction hearing in the Hong Kong High Court on November 21, 2023. Following the injunction hearing on November 21, 2023, the Company will re-assess promptly whether to convene a special meeting.

About Hollysys Automation Technologies Ltd.

Hollysys is a leading automation control system solutions provider in China, with overseas operations in eight other countries and regions throughout Asia. Leveraging its proprietary technology and deep industry know-how, Hollysys empowers its customers with enhanced operational safety, reliability, efficiency, and intelligence which are critical to their businesses. Hollysys derives its revenues mainly from providing integrated solutions for industrial automation and rail transportation. In industrial automation, Hollysys delivers the full spectrum of automation hardware, software, and services spanning field devices, control systems, enterprise manufacturing management and cloud-based applications. In rail transportation, Hollysys provides advanced signaling control and SCADA (Supervisory Control and Data Acquisition) systems for high-speed rail and urban rail (including subways). Founded in 1993, with technical expertise and innovation, Hollysys has grown from a research team specializing in automation control in the power industry into a group providing integrated automation control system solutions for customers in diverse industry verticals. As of June 30, 2023, Hollysys had cumulatively carried out more than 45,000 projects for approximately 23,000 customers in various sectors including power, petrochemical, high-speed rail, and urban rail, in which Hollysys has established leading market positions.

Safe Harbor Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact included herein are "forward-looking statements," including statements regarding the ability of the Company to achieve its commercial objectives; the business strategy, plans and objectives of the Company; growth in financial and operational performance of the Company; and any other statements of non-historical information. These forward-looking statements are often identified by the use of forward-looking terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," "target," "confident," or similar expressions involve known and unknown risks and uncertainties. Such forward-looking statements, based upon the current beliefs and expectations of Hollysys’ management, are subject to risks and uncertainties, which could cause actual results to differ from the forward-looking statements. Although the Company believes that the expectations reflected in these forward-looking statements are reasonable, they do involve assumptions, risks and uncertainties, and these expectations may prove to be incorrect. Investors should not place undue reliance on these forward-looking statements, which speak only as of the date of this press release. The Company’s actual results could differ materially from those anticipated in these forward-looking statements as a result of a variety of factors, including those discussed in the Company’s reports that are filed with the Securities and Exchange Commission and available on its website (http://www.sec.gov). All forward-looking statements attributable to the Company or persons acting on its behalf are expressly qualified in their entirety by these factors. Other than as required under the securities laws, the Company does not assume a duty to update these forward-looking statements.

Contact Information

Company Contact:
Hollysys Automation Technologies Ltd.
www.hollysys.com
+8610-5898-1386
[email protected] 

Media Contacts (Hong Kong and New York):
Brunswick Group
[email protected] 

Emily Wong (Hong Kong)
[email protected]
+852 6627 8297

Libby Lloyd (New York)
[email protected]
+1 347 283 3871

Source : Hollysys Provides Update on Sale Process; Responds to Shareholder Request for Special Meeting

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FUZHOU, China, Oct. 30, 2023 /PRNewswire/ — In the afternoon of 28 October, the opening ceremony of the 2023 China Observance of World Cities Day witnessed the announcement of winners of the first Global Award for Sustainable Development in Cities (Shanghai Award). Fuzhou, a China’s southeastern city, was honored alongside Australia’s Brisbane, Malaysia’s George Town, Uganda’s Kampala, and Brazil’s Salvador with this prestigious recognition.

Recently, the award-winning promotional posters have been showcased on the window screens of the ORIENTAL.PARIS in France, as well as on outdoor screens in five Chinese cities: Beijing, Shanghai, Guangzhou, Shenzhen, and Fuzhou, according to the Publicity Department of CPC Fuzhou Municipal Committee. This piece of delightful news is being shared with people at home and aboard.

Fuzhou has made remarkable strides in various areas, including prioritising sustainable development strategies in green and digital economies, implementing innovative urban water system management projects, and constructing an environmentally friendly, low-carbon, and ecologically sustainable "City of Parks".

With outstanding air quality of 97.5% good and excellent AQI throughout the year, over 1,400 parks spread across the city, and a per capita park green space area of 14.83 square meters, Fuzhou is committed to a green and ecological foundation for top-notch development. The city places great importance on protecting the ecological environment, promoting energy-saving and carbon reduction measures, advocating for a green lifestyle, and driving the transition towards a green and low-carbon approach to development.

Furthermore, Fuzhou is actively promoting digital industrialisation and industrial digitisation, with a strong focus on developing the digital economy and establishing the renowned "Digital Fuzhou" brand. In 2022, the scale of Fuzhou’s digital economy surpassed USD 85.7 billion, accounting for more than 50% of its GDP. This robust growth in the digital economy has infused Fuzhou’s urban development with renewed energy and significant momentum.

Moving forward, Fuzhou remains committed to sustainable development as it builds itself into a modern international city. The city will persistently seek innovative approaches to foster a livable, resilient, and smart city development, ultimately enhancing the well-being of its residents.

Image Attachments Links:

   Link: https://iop.asianetnews.net/view-attachment?attach-id=442949 

   Caption: Award-winning promotional poster

Source : Fuzhou, China Honored with First Global Award for Sustainable Development in Cities

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BEIJING, Oct. 30, 2023 /PRNewswire/ — WiMi Hologram Cloud Inc. (NASDAQ: WIMI) ("WiMi" or the "Company"), a leading global Hologram Augmented Reality ("AR") Technology provider, today announced that a breakthrough solution for assembly and manipulation using hand-guiding based on brain-computer interface has been developed, opening up a new perspective in the field of production.

Traditional production processes often require a great deal of physical effort and energy from operators, especially in environments with complex and repetitive tasks, which can easily lead to increased operator fatigue and errors. The introduction of collaborative robots has opened up a whole new set of opportunities for organizations. With their compact size and programmable nature, collaborative robots are able to perform diverse tasks and can reduce operator workload and increase productivity. For small and medium-sized businesses in particular, the introduction of this technology will be a major competitive advantage.

In order to realize efficient communication and cooperation between humans and collaborative robots, a key issue is how to design appropriate tasks and interaction strategies. This brain-computer interface-based assembly and hand-guided control technology from WiMi focuses on collaborative assembly tasks. To solve this problem, WiMi proposes a brain-computer interface-based strategy that realizes operator command control of collaborative robots through brain-computer interface technology.

Brain-computer interface technology plays a key role in WiMi’s brain-computer interface-based assembly and manipulation using hand-guiding technology. Brain-computer interface (BCI) is a technology that works by detecting brain activity and translating it into computer-understandable instructions. In this technology, the operator is enabled to send commands to the collaborative robot through the steady-state visual evoked potential (SSVEP). This approach enables the operator to switch between task modes without using his hands. In addition, the technique introduces hand-guided control, which is realized by installing a six-component force sensor on the wrist of the collaborative robot.

Task switching and phase synchronization are critical throughout the production assembly process. WiMi’s brain-computer interface-based assembly and manipulation using hand-guiding technology divides the collaborative process into an independent phase and a support phase. In the independent phase, the robot and the operator work together to accomplish a variety of different work tasks. Once the operator needs the help of the robot, he or she can switch to the support phase to realize the human-robot cooperative operation. This switching is realized by the operator sending command messages in the BCI, thus informing the robot in advance of the intention to switch.

The operator can interact with the collaborative robot through the interface. In terms of BCI-related activities, the operator realizes the control of the robot by observing images, and these commands are referenced to the robot controller after electrodes are collected and processed. On the other hand, with manual guidance control, the operator can realize guidance control of the robot through sensors on the robot’s wrist. The entire assembly process depends on pre-programmed robot subtasks and commands issued by the operator in real time.

The entire process between the transmission of the operator’s commands to the actual actions of the collaborative robot. This process involves multiple steps and technologies to ensure that the operator’s intent is accurately translated into the robot’s behavior, resulting in efficient human-robot cooperation.

Applications of BCI: Brain-computer interface technology is at the heart of the technology pathway. In this technology, the operator’s brain activity is captured and transformed into computer-understandable commands that enable control of the collaborative robot. WiMi’s brain-computer interface-based assembly and manipulation using hand-guiding technology, brain-computer interface technology is applied through SSVEP to realize the switching between different task modes.

Data collection and processing: The first step in the technology pathway is data acquisition and processing of the operator’s brain activity. This involves placing electroencephalography (EEG) electrodes on the operator’s head to capture the electrical signals generated by the brain. These electrical signals are then transmitted to a computer for processing to extract information about the operator’s intentions.

Command generation and transmission: By analyzing the electrical signals generated by the operator’s brain, the computer can generate appropriate commands. These commands represent the operator’s intention to switch task modes. These commands need to be delivered to the control system of the collaborative robot to achieve control of the robot’s behavior.

Manipulation using hand-guided: In another branch of this technology path, manual guidance control technology is applied to achieve more precise control. Collaborative robots are realized utilizing hexagonal force sensors. The sensors sense the guiding force of the operator’s hand and transmit this information to the robot control system.

Control and execution: Commands generated by BCI technology and information delivered by manually guided control technology are ultimately executed by the robot’s control system. The robot realizes different task mode switching according to the operator’s intention and thus operates collaboratively in different phases.

Feedback and synchronization: The final step in the technology display path involves feedback and synchronization. Once the robot performs the appropriate action, feedback can be passed on to the operator to ensure that the operator is aware of the robot’s behavior and state. This helps the operator to further fine-tune their communication of intent, leading to better human-robot cooperation.

Every aspect of the process, from brain-computer interface to hand-guided control, requires a defined division of labor and implementation to ensure efficient and precise human-machine cooperation. The successful development of this innovative technology opens up new possibilities for modern manufacturing and will enhance productivity, reduce operator burden and play an active role in small and medium-sized enterprises.

WiMi’s brain-computer interface-based assembly and manipulation using hand-guiding technology provides unprecedented opportunities for small and medium-sized businesses. By combining brain-computer interface technology with hand-guided control technology, operators can precisely control and guide robots without the need to use their hands. This greatly improves the efficiency and quality of the production process, reduces the burden on operators, lowers the error rate, and marks a new stage in modern manufacturing.

About WIMI Hologram Cloud

WIMI Hologram Cloud, Inc. (NASDAQ: WIMI) is a holographic cloud comprehensive technical solution provider that focuses on professional areas including holographic AR automotive HUD software, 3D holographic pulse LiDAR, head-mounted light field holographic equipment, holographic semiconductor, holographic cloud software, holographic car navigation and others. Its services and holographic AR technologies include holographic AR automotive application, 3D holographic pulse LiDAR technology, holographic vision semiconductor technology, holographic software development, holographic AR advertising technology, holographic AR entertainment technology, holographic ARSDK payment, interactive holographic communication and other holographic AR technologies.

Safe Harbor Statements

This press release contains "forward-looking statements" within the Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," and similar statements. Statements that are not historical facts, including statements about the Company’s beliefs and expectations, are forward-looking statements. Among other things, the business outlook and quotations from management in this press release and the Company’s strategic and operational plans contain forward−looking statements. The Company may also make written or oral forward−looking statements in its periodic reports to the US Securities and Exchange Commission ("SEC") on Forms 20−F and 6−K, in its annual report to shareholders, in press releases, and other written materials, and in oral statements made by its officers, directors or employees to third parties. Forward-looking statements involve inherent risks and uncertainties. Several factors could cause actual results to differ materially from those contained in any forward−looking statement, including but not limited to the following: the Company’s goals and strategies; the Company’s future business development, financial condition, and results of operations; the expected growth of the AR holographic industry; and the Company’s expectations regarding demand for and market acceptance of its products and services.

Further information regarding these and other risks is included in the Company’s annual report on Form 20-F and the current report on Form 6-K and other documents filed with the SEC. All information provided in this press release is as of the date of this press release. The Company does not undertake any obligation to update any forward-looking statement except as required under applicable laws.

Contacts
WIMI Hologram Cloud Inc.
Email: [email protected]
TEL: 010-53384913

ICR, LLC
Robin Yang
Tel: +1 (646) 975-9495
Email: wimi@icrinc.com

Source : WiMi Developed Brain-Computer Interface-Based Assembly and Manipulation using Hand-Guiding

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LONDON, Oct. 31, 2023 /PRNewswire/ — Patrick Racz, founder, and inventor of Smartflash, has announced a lawsuit filed by Smartflash against the United States Patent and Trademark Office (USPTO) in connection with Smartflash’s ongoing Civil RICO investigation into Apple.

The Racketeer Influenced and Corrupt Organizations Act (RICO) is a federal law that allows for the prosecution of individuals or organizations engaged in illegal activities as part of a larger criminal enterprise.

In 2015, Racz won a resounding victory against Apple in court, with an initial jury award of $533 million for wilful infringement. The key merits and findings of the case, namely that Apple infringed on the technology and induced others to infringe, remain undisturbed today.

From 2015 to 2018, Racz was then forced to defend a series of costly appeals in separate forums, including 48 individual cases at the Patent Trial Appeal Board (PTAB), where the panels of judges were stacked and comprised of ex lawyers for the defendants, including Apple.

"We have been fighting the US Patent Office tooth and nail for the past 3 years, to obtain copies of multiple unredacted emails and documents that we are fully entitled to receive but have been left with no choice other than suing them" said Racz. "We are committed to protecting our intellectual property and will not rest until justice has been served."

The complaint explains that the USPTO has withheld multiple unredacted documents requested by Smartflash under the Freedom Of Information Act (FOIA), as part of a "pattern or practice" that impermissibly delays Smartflash’s access to relevant government records, that prevents Smartflash from continuing its multi-year investigations into PTAB panel manipulation & panel stacking, evidence of how Smartflash was treated at the USPTO and how the USPTO is falsely claiming deliberative process privilege where none existed.

The complaint explains why the withholding of documents relating to these cases at the PTAB are a matter of great public importance, citing Supreme Court Justice Gorsuch’s Opinion in United States v. Arthrex, Inc., 141 S. Ct. 1970, 1993 (2021) and referring to the Apple v Smartflash cases at the PTAB, where former Apple patent defence attorney Matt Clements presided over cases involving his former employer Apple.

For more information or to request an interview contact [email protected] or call Charles Carroll on +44 (0) 20 3176 2700.

For more information about the campaign, visit www.patrickracz.com

Source : Smartflash sues US Patent Office in ongoing Apple Racketeering Investigation

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HONG KONG, Oct. 30, 2023 /PRNewswire/ — Akeso (9926.HK) announced that the results of a phase Ib clinical trial for PD-1/VEGF bispecific antibody ( ivonecimab AK112/SMT112 ) as first- or second-line therapy for advanced or metastatic immunotherapy naïve non-small-cell lung cancer (NSCLC) were published in the Journal of Thoracic Oncology (JTO), the official journal of the International Association for the Study of Lung Cancer (IASLC). The principal investigator of this study is Prof. Caicun Zhou, MD, PhD, from Shanghai Pulmonary Hospital, affiliated with Tongji University.

Previously, the clinical results of ivonescimab in combination with chemotherapy for NSCLC were published in the eClinical Medicine (part of The Lancet). The monotherapy results published in JTO represents another significant recognition of the clinical value of ivonescimab.

The phase Ib study, published in JTO, aims to determine the optimal dose, safety, and efficacy of ivonescimab monotherapy as a first- or second-line treatment for advanced NSCLC patients. Early data on ivonescimab in NSCLC was also presented at the 2022 American Society of Clinical Oncology (ASCO) meeting.

From the data published in JTO, patients with advanced or metastatic NSCLC can benefit from ivonescimab monotherapy regardless of treatment dosage, prior treatment history, and PD-L1 expression. This data was based on a median follow-up of 10.4 months (as of October 5, 2022). Furthermore, updated data from the study (with a median follow-up of 19.3 months) as of June 30, 2023 demonstrates the increased safety and survival benefits of ivonescimab monotherapy.

Currently, following an acceptance of the marketing application with priority review of ivonescimab by the Center for Drug Evaluation (CDE) of the China National Medical Products Administration (NMPA), four registrational phase III clinical trials have been initiated/are being conducted worldwide, including three head-to-head trials with PD-1 monoclonal antibody as the positive control drug, and two international multicenter clinical trials.

About Ivonescimab (PD-1/VEGF bispecific antibody)

Ivonescimab is a potential first-in-class investigational PD-1/VEGF bi-specific antibody discovered by Akeso and is believed to be the PD-1 / VEGF bispecific antibody that is most advanced in the clinic. It combines the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab is currently engaged in multiple Phase III clinical trials worldwide.

In December 2022, Akeso entered into a collaboration and license agreement for up to US$5 billion with Summit Therapeutics ("Summit"). Akeso out-licensed to Summit exclusive rights to ivonescimab (PD-1/VEGF) for the development and commercialization in the United States, Canada, Europe, and Japan. Akeso will retain development and commercialization rights for the rest of the world including China. Ivonescimab is known as AK112 for Akeso’ R&D code at China and Australia, and as SMT112 for Summit’s license territories.

About Akeso, Inc.

Akeso (HKEX: 09926) is a commercial-stage biopharmaceutical company committed to discovering, developing, manufacturing, and commercializing innovative medicines that address significant medical needs globally. Since our inception , we have established a distinctive and integrated R&D innovation system with the comprehensive end-to-end drug development platform (ACE Platform) and bi-specific antibody drug development technology (Tetrabody) as the fundamental components, a GMP-compliant manufacturing system and a commercialization system with an advanced operation mode.

Akeso is actively developing a diverse pipeline of over 30 innovative assets in areas such as cancer, autoimmune disease, inflammation, metabolic disease, and other therapeutic fields. Among these, 19 assets have entered the clinical stage, with 3 innovative drugs already approved, NDAs for 4 drugs and 6 indications accepted, and 13 ongoing Phase III studies. Utilizing its proprietary Tetrabody technology, Akeso has successfully developed the first-in-class PD-1/CTLA-4 bispecific antibody drug to the market. Additionally, the company has five other innovative bispecific antibody drugs in the clinical stage, including ivonescimab (PD-1/VEGF), PD-1/LAG-3, TIGIT/TGF-Beta, PD-1/CD73, and claudin18.2/CD47 bispecific antibodies.

In June 2022, cadonilimab was approved by the NMPA and became the first commercialized bispecific IO drug globally. Another Akeso internally discovered and developed oncology product, penpulimab (a PD-1 antibody), was granted marketing approval in China in August 2021. In December 2022, Akeso entered into a collaboration and license agreement for up to US$5 billion with Summit Therapeutics to accelerate global development and commercialization of ivonescimab. In August, the NDA submission of ivonescimab was accepted by China’s NMPA and granted Priority Review. Akeso is listed on the Main Board of the Stock Exchange of Hong Kong Limited.

Contact Akeso Public Relations:
[email protected]

Contact Akeso Business Development :
[email protected]

Source : Journal of Thoracic Oncology Published Promising Results of Ivonescimab (PD-1/VEGF Bispecific) as First- or Second-line Therapy for Advanced or Metastatic Immunotherapy Naïve Non-Small-Cell Lung Cancer

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NORWALK, Conn., Oct. 31, 2023 /PRNewswire/ — LifeSpan Vision Ventures, an investment firm dedicated to longevity biotech, today announced an investment in NaNotics LLC. This preclinical-stage biopharmaceutical company is developing NaNots™, novel subtractive nanoparticles that treat disease by capturing and clearing pathogenic molecules from blood. NaNots™ differ from traditional drug therapies in their ability to deplete soluble targets without interacting with the membrane forms of the same target, a feat that is typically beyond the reach of conventional drugs.

LifeSpan Vision Ventures Invests in NaNotics

The company is advancing a pipeline of NaNots targeting oncology and inflammatory markers associated with multiple diseases that present substantial unmet medical needs. Additionally, they have announced research collaborations with Mass General Cancer Clinic, situated within Mass General Hospital, and Mayo Clinic to further enhance their therapies for specific oncology targets.

Harry Robb, Analyst at LifeSpan Vision Ventures commented: "With our first investment in the nanomedicine field, we are partnering with NaNotics, a California-based biopharmaceutical company with a vision of depleting soluble targets from blood to treat a range of diseases – and potentially aging as well. The company is backed by a dedicated and highly experienced team that is committed to leading a shift in medicine from a cell-based focus to a signal-based focus. This represents an exciting opportunity to expand treatment options and we see a great potential in their transformative therapies to have a meaningful impact on patient outcomes."

Lou Hawthorne, CEO of NaNotics and the inventor of NaNots, commented, "Lifespan Vision Ventures is an ideal investor for us, for reasons that go beyond capital. They understand that aging is potentially driven by soluble factors that also drive or enable FDA-recognized diseases, and that NaNots can therefore address both. This provides a viable FDA approval path for a therapeutic platform to address aging – which the FDA does not recognize as a disease. We look forward to collaborating with Lifespan Vision Ventures to develop and market therapeutics for treating disease and extending healthspan for all people."

About NaNotics LLC
NaNotics LLC is a preclinical stage company based in Mill Valley, CA. The company is developing a pipeline of NaNots™ against a range of oncology and inflammatory targets driving multiple diseases representing significant unmet medical need.

For more information, please visit https://www.nanotics.com/
Contact: Song Schreiber, CFO: [email protected]

About LifeSpan Vision Ventures
LifeSpan Vision Ventures is a forward-thinking venture capital firm specializing in investments within the aging and longevity space. Our mission is to support and accelerate the development of innovative therapies that extend healthspan, improve the quality of life for individuals as they age, and address age-related challenges. Through strategic partnerships and investments, we aim to shape a future where aging is met with vitality, resilience, and endless possibilities.

For more information about LifeSpan Vision Ventures, please visit https://www.lifespanvisionventures.com/.

Contact: Harry Robb
mob: +44 7795042764
[email protected]

Source : LifeSpan Vision Ventures Invests in NaNotics

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